^AXLung-on-Chip System

Technology information

With the ^AXLung-on-Chip System, healthy, diseased, and personalized in-vitro models can be create to test molecule safety, efficacy, and toxicity (drugs, pollutants, cosmetics, etc.) as well as to answer fundamental research questions. Based on this system, we have developed a wide range of different applications, see  ^AXBiomodels.

Key Features

The ^AXLung-on-Chip System replicates the key features of the human lung microenvironment for in vitro modelling in outmost physiological conditions:

• Ultrathin, porous and elastic membrane for cell growth
  Thickness: 3.5µm & Pores: Ø 3µm
• Breathing motion
  12 cycles/min & 8% linear strain
• Mono- or Coculture models
  with/without immune component​​
• Air-liquid interface
  Ideal for exposure or inhalation studies​