The Cloud α AX12 platform emerges as a transformative tool in inhalation research, providing human-relevant insights into toxicity mechanisms, susceptibility factors, and therapeutic responses. The system is equipped with a Quartz crystal microbalance allowing you to accurately know the dosimetry of your nanoparticles on top of your cells. Our AX12 plate can be internally connected to the actuation controller allowing the dynamic stretch of your cells while being exposed to cloud. Our innovative approach not only elevates precision and relevance in inhalation studies but also sets a benchmark for ethical and scientifically robust research methodologies.  

Options:   

• Continuous flow 

• Dry powder 

• Nebulizer  

Some studies: 

• Environmental triggers (aerosolized nanoparticles or biocides) 

• Drug efficacy  

• Smoke, e-cigarettes 

Organs disorders can be modelled by including trigger molecules that induce relevant disease endpoints or by using cells from diseased tissue. Disease models are internally validated using approved drugs by proving their beneficial rescue effect towards healthy status. Test candidates can be benchmarked against existing approved drugs or failed candidates. Our efficacy models predict the effect of potential drug candidates in preclinical phases, allow to identify new therapeutic targets, and can be applied for personalized medicine approaches.  

Previous : 

• Acute toxicity & inflammation ( ARDS, Acute Lung Injury , Heme-driven lung toxicity ) 

• Infection models  (Bacterial infection, Viral infection) 

• Interstitial lung diseases  (Lung fibrosis, COPD) 

• Inflammatory Bowel Disease 

• Lung Inflammation (PHMG, LPS, TNFα) 

• Smoke-induced inflammation

The Cloud α AX12 platform emerges as a transformative tool in inhalation research, providing human-relevant insights into toxicity mechanisms, susceptibility factors, and therapeutic responses. The system is equipped with a Quartz crystal microbalance allowing you to accurately know the dosimetry of your nanoparticles on top of your cells. Our AX12 plate can be internally connected to the actuation controller allowing the dynamic stretch of your cells while being exposed to cloud. Our innovative approach not only elevates precision and relevance in inhalation studies but also sets a benchmark for ethical and scientifically robust research methodologies.  

Options:   

• Continuous flow 

• Dry powder 

• Nebulizer  

Some studies: 

• Environmental triggers (aerosolized nanoparticles or biocides) 

• Drug efficacy  

• Smoke, e-cigarettes