News

June 26, 2023 Launch of AX Cells-on-Chip
March 16, 2023 Launch of New Organ-on-Chip System
February 19, 2023 1st face-to-face meeting for EPIColiX project
January 4, 2023 The FDA Modernization Act 2.0 passed

News

June 26, 2023 Launch of AX Cells-on-Chip
March 16, 2023 Launch of New Organ-on-Chip System
February 19, 2023 1st face-to-face meeting for EPIColiX project
January 4, 2023 The FDA Modernization Act 2.0 passed

Events

June 20, 2023 MPS World Summit 2023
March 9, 2023 SOT 2023
February 22, 2023 SLAS 2023
December 5, 2022 Panel discussion with our co-CEO Nina Hobi

Events

June 20, 2023 MPS World Summit 2023
March 9, 2023 SOT 2023
February 22, 2023 SLAS 2023
December 5, 2022 Panel discussion with our co-CEO Nina Hobi

Publications

August 19, 2022 A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System

Frontiers in Toxicology Sengupta, A., Roldan, N., Kiener, M., Froment, L., Raggi, G., Imler, T., de Maddalena, L., Rapet, A., May, T., Carius, P., Lehr, C., Geiser, T., Marti, T. M., Stucki, J. D., Hobi, N., & Guenat, O. T. Abstract The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the…

May 7, 2021 Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19

Frontiers in Medicine

October 28, 2020 Modelling alveoli on a breathing lung-on-chip in health and disease

European Respiratory Journal

October 28, 2020 Organoids and lung-on-chip to study SARS-CoV-2-mediated lung injury

European Respiratory Journal

Publications

August 19, 2022 A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System

Frontiers in Toxicology Sengupta, A., Roldan, N., Kiener, M., Froment, L., Raggi, G., Imler, T., de Maddalena, L., Rapet, A., May, T., Carius, P., Lehr, C., Geiser, T., Marti, T. M., Stucki, J. D., Hobi, N., & Guenat, O. T. Abstract The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the…

May 7, 2021 Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19

Frontiers in Medicine

October 28, 2020 Modelling alveoli on a breathing lung-on-chip in health and disease

European Respiratory Journal

October 28, 2020 Organoids and lung-on-chip to study SARS-CoV-2-mediated lung injury

European Respiratory Journal

October 28, 2020

Interleukin-2 – induced vascular leak syndrome: clinically relevant in vitro recapitulation with a patient-derived lung-on-chip

European Respiratory Journal

October 28, 2020

Modeling alveolar barrier disruption in vitro for sepsis-induced ARDS preclinical studies

European Respiratory Journal

May 05, 2020

Alveolar Dynamics and Beyond – The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis

Frontiers in Physiology

April 02, 2020

CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung

AJP Lung Cell and Molecular Physiology

January 21, 2020

Clinically relevant tissue scale responses as new readouts from organs-on-a-chip for precision medicine

Annual Review of Analytical Chemistry

January 15, 2020

Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls

Respiratory Research 

January 10, 2020

Air Space Distension Precedes Spontaneous Fibrotic Remodeling and Impaired Cholesterol Metabolism in the Absence of Surfactant Protein C

AJR Cell and Molecular Biology

January 10, 2020

Air space distension precedes spontaneous fibrotic remodeling and impaired cholesterol metabolism in the absence of Surfactant Protein C

American Journal of Respiratory Cell and Molecular Biology

November 21, 2019

Investigating the toxicological potential of inhaled aerosols in a breathing lung-on-chip

European Respiratory Journal

November 21, 2019

A lung-on-chip in vitro approach to study inflammation at the alveolar level

European Respiratory Journal

September 06, 2019

Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline

European Journal of Pharmaceutics and Biopharmaceutics

May 24, 2019

Nanoparticle exposure on a breathing alveolus‐on‐chip

Journal of Aerosol Medicine and Pulmonary Drug Delivery

January 22, 2019

Impaired wound healing of alveolar lung epithelial cells in a breathing lung-on-a-chip

Frontiers in Bioengineering and Biotechnology. Tissue Engineering and Regenerative Medicine 

December 27, 2018

Tumor initiation capacity and therapy resistance are differential features of EMT-related subpopulations in the NSCLC cell line A549

Neoplasia

November 01, 2018

Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro

Angiogenesis

October 10, 2018

Lung-on-a-Chip: The interplay of primary human epithelial and endothelial cells improves the alveolar barrier function

Toxicology Letters

October 10, 2018

Acute lung injury on-chip: building a disease predictive model that emulates alveolar biomechanics

Toxicology Letters

September 25, 2018

Medium throughput breathing human primary cell alveolus-on-chip model

Scientific Reports

May 21, 2018

Incorporating mechanical strain in organs-on-a-chip: Lung and skin

Biomicrofluidics

Media

April 21, 2022 Great expectations for miniature lungs
April 11, 2022 More and more startups in healthcare
March 21, 2022 Advanced inhalation model with the AXLung-on-Chip System
March 10, 2022 What is the impact of the 3D stretch?