Approximately 95% of drugs that are effective and safe in animal experiments fail in human clinical trials. This high failure rate is mostly explained by the fact that these tests are carried out in a different organism, and hence translation to humans is not straightforward.
PETA has been committed for years to provide contrasted data supporting reliable in vitro and in silico-based methods as an alternative to animal testing. In this article by Handelsblatt, Anne Meinert from PETA explains why organ-on-chip technology is a great alternative to animal experimentation.