Publications
Mar 17, 2025
Autologous human iPSC-derived Alveolus-on-Chip reveals earlypathological events of M. tuberculosis infection
BioRxiv Chak Hon Luk, Gabriel L. Conway, Kim Jee Goh, Antony Fearns, Irene Rodriguez-Hernandez, Nathan J. Day, Natalia Athanasiadi, Rocco D’Antuono, Enrica Pellegrino, Janick D. Stucki, Nina Hobi, Maximiliano G. Gutierrez AbstractImmunocompetent and experimentally accessible alveolar systems to study human respiratory diseases are lacking. Here, we developed a single donor human induced pluripotent stem cell...
Jan 31, 2025
The Use of MPS in 3Rs and Regulatory Applications: Perspectives from Developers on Stakeholder Responsibilities
Sage Journals Megan R. LaFollette, Szczepan W. Baran, J. Lowry Curley, Anne M. Dickinson, Trivia Frazier, Nina Hobi, Ming-I Huang, Victoria Hutter, Benoît G.C. Maisonneuve, Graham A. Marsh, Rhamiya Mahendran, Iris Müller, Xiaohua Qian, Dharaminder Singh, William R. Thelin, Jelena Vukasinovic, Pelin L. Candarlioglu and Clive S. Roper Abstract Increasing the use of microphysiological systems...
Oct 17, 2024
A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug response
Bioengineering & Translational Medecine Clémentine Richter, Lorenz Latta, Daria Harig, Patrick Carius, Janick D. Stucki, Nina Hobi, Andreas Hugi, Paul Schumacher, Tobias Krebs, Alexander Gamrekeli, Felix Stöckle, Klaus Urbschat, Galia Montalvo, Franziska Lautenschläger, Brigitta Loretz, Alberto Hidalgo, Nicole Schneider-Daum, Claus-Michael Lehr AbstractThis study describes a complex human in vitro model for evaluating anti-inflammatory drug response...
Apr 16, 2024
The physiological interactome of TCR-like antibody therapeutics in human tissues
Nature Communications Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac Woodhouse, Alexander Bujotzek , Christian Klein & Nicola Ternette Abstract Selective binding of...
