News
News
November 18, 2024
AlveoliX on SRFOctober 03, 2024
AlveoliX Joins PANC-CKI ConsortiumJune 04, 2024
Partnership to Pioneer Ulcerative Colitis TreatmentApril 02, 2024
Podcast on X-health.showMarch 12, 2024
New quantum computers – Potential and pitfallsMarch 05, 2024
Celebrating 5 Years of DedicationDecember 10, 2023
Video & Article – Future of Ethical ResearchJune 26, 2023
Launch of AX Cells-on-ChipJune 07, 2023
AlveoliX on AirMarch 16, 2023
Launch of New Organ-on-Chip SystemFebruary 19, 2023
1st face-to-face meeting for EPIColiX projectJanuary 04, 2023
The FDA Modernization Act 2.0 passedNovember 24, 2022
Aude Rapet won the ecopa Award at ESTIV 22October 25, 2022
EUSAAT Summary of latest technologiesOctober 04, 2022
FDAÂ Modernization Act 2.0 has passed the US SenateSeptember 08, 2022
Open letter for the FDA Modernization ActJuly 27, 2022
AlveoliX is part of the 2022 Lush Prize shortlistJune 14, 2022
AlveoliX winner of the Swiss Medtech Award 2022May 25, 2022
Close collaboration with CSL and Insel GruppeEvents
Events
May 05, 2025
SwissBiotech Day 2025March 16, 2025
SOT 2025February 13, 2025
CSEM NextGenOOC 2025July 03, 2024
EUROoCs 2024June 10, 2024
MPS World Summit 2024June 03, 2024
ESTIV Congress 2024March 10, 2024
SOT 2024February 03, 2024
SLAS 2024November 24, 2023
3R Austrian DaysSeptember 28, 2023
BioJapan 2023September 08, 2023
EUROTOX 2023August 24, 2023
WC12August 15, 2023
ISAM 2023August 08, 2023
Next-Gen Organ-On-Chip & Organoids WorkshopJune 20, 2023
MPS World Summit 2023March 09, 2023
SOT 2023February 22, 2023
SLAS 2023December 05, 2022
Panel discussion with our co-CEO Nina HobiDecember 02, 2022
BSTE 2022 SymposiumPublications
BioRxiv Mirjam Kiener, Lea Lara De Maddalena, Nuria Roldan, Panagiotis Chouvardas, Laurène Froment, Marta De Menna, Thomas Geiser, Janick Stucki, Nina Hobi, Marianna Kruithof-de Julio Abstract: Respiratory viruses pose a constant threat to public health as highlighted by the pandemic outbreak of COVID-19. The most severe manifestation of COVID-19 is observed in the distal lung,…
Scientific Reports, Nature Arunima Sengupta, Saskia Schmid, NoĂ©mie Grangier, AurĂ©lien Dorn, Marco Hebestreit, Andreas Hugi, KristĂna Ĺ˝ajdlĂková, Anja Herbst, Paula Losada-Oliva, Heidi Ortolf-Wahl, Philippe Krebs, Janick D. Stucki, Vera van der Velpen, Jesus Perez-Gil, Tobias Krebs, Nina Hobi & Olivier T. Guenat Abstract: Continuous exposure to cigarette smoke (CS) significantly contributes to the development and…
BioRxiv Fabio Palmieri, AurĂ©lien Trompette, Apiha Shanmuganathan, Aureline Bouchard, Julie Pernot, Thomas Junier, Julia M. Kelliher, Patrick S.G. Chain, Jennifer Foster Harris, Armelle Vallat, Marco Pagni, Christophe von Garnier, Janick D. Stucki, Nina Hobi, Angela Koutsokera, Samuel Neuenschwander, Niki D. Ubags, Pilar Junier Abstract: Aspergillus fungi are opportunistic pathogens that affect millions of people worldwide.…
BioRxiv Chak Hon Luk, Gabriel L. Conway, Kim Jee Goh, Antony Fearns, Irene Rodriguez-Hernandez, Nathan J. Day, Natalia Athanasiadi, Rocco D'Antuono, Enrica Pellegrino, Janick D. Stucki, Nina Hobi, Maximiliano G. Gutierrez AbstractImmunocompetent and experimentally accessible alveolar systems to study human respiratory diseases are lacking. Here, we developed a single donor human induced pluripotent stem cell…
Publications
BioRxiv Mirjam Kiener, Lea Lara De Maddalena, Nuria Roldan, Panagiotis Chouvardas, Laurène Froment, Marta De Menna, Thomas Geiser, Janick Stucki, Nina Hobi, Marianna Kruithof-de Julio Abstract: Respiratory viruses pose a constant threat to public health as highlighted by the pandemic outbreak of COVID-19. The most severe manifestation of COVID-19 is observed in the distal lung,…
Scientific Reports, Nature Arunima Sengupta, Saskia Schmid, NoĂ©mie Grangier, AurĂ©lien Dorn, Marco Hebestreit, Andreas Hugi, KristĂna Ĺ˝ajdlĂková, Anja Herbst, Paula Losada-Oliva, Heidi Ortolf-Wahl, Philippe Krebs, Janick D. Stucki, Vera van der Velpen, Jesus Perez-Gil, Tobias Krebs, Nina Hobi & Olivier T. Guenat Abstract: Continuous exposure to cigarette smoke (CS) significantly contributes to the development and…
BioRxiv Fabio Palmieri, AurĂ©lien Trompette, Apiha Shanmuganathan, Aureline Bouchard, Julie Pernot, Thomas Junier, Julia M. Kelliher, Patrick S.G. Chain, Jennifer Foster Harris, Armelle Vallat, Marco Pagni, Christophe von Garnier, Janick D. Stucki, Nina Hobi, Angela Koutsokera, Samuel Neuenschwander, Niki D. Ubags, Pilar Junier Abstract: Aspergillus fungi are opportunistic pathogens that affect millions of people worldwide.…
BioRxiv Chak Hon Luk, Gabriel L. Conway, Kim Jee Goh, Antony Fearns, Irene Rodriguez-Hernandez, Nathan J. Day, Natalia Athanasiadi, Rocco D'Antuono, Enrica Pellegrino, Janick D. Stucki, Nina Hobi, Maximiliano G. Gutierrez AbstractImmunocompetent and experimentally accessible alveolar systems to study human respiratory diseases are lacking. Here, we developed a single donor human induced pluripotent stem cell…
January 31, 2025
The Use of MPS in 3Rs and Regulatory Applications: Perspectives from Developers on Stakeholder ResponsibilitiesSage Journals Megan R. LaFollette, Szczepan W. Baran, J. Lowry Curley, Anne M. Dickinson, Trivia Frazier, Nina Hobi, Ming-I Huang, Victoria Hutter, BenoĂ®t G.C. Maisonneuve, Graham A. Marsh, Rhamiya Mahendran, Iris MĂĽller, Xiaohua Qian, Dharaminder Singh, William R. Thelin, Jelena Vukasinovic, Pelin L. Candarlioglu and Clive S. Roper Abstract Increasing the use of microphysiological systems…
October 17, 2024
A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug responseBioengineering & Translational Medecine ClĂ©mentine Richter, Lorenz Latta, Daria Harig, Patrick Carius, Janick D. Stucki, Nina Hobi, Andreas Hugi, Paul Schumacher, Tobias Krebs, Alexander Gamrekeli, Felix Stöckle, Klaus Urbschat, Galia Montalvo, Franziska Lautenschläger, Brigitta Loretz, Alberto Hidalgo, Nicole Schneider-Daum, Claus-Michael Lehr AbstractThis study describes a complex human in vitro model for evaluating anti-inflammatory drug response…
April 16, 2024
The physiological interactome of TCR-like antibody therapeutics in human tissuesNature Communications Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac Woodhouse, Alexander Bujotzek , Christian Klein & Nicola Ternette Abstract Selective binding of…
March 06, 2023
A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chipFrontiers in Pharmacology Sengupta A, Dorn A, Jamshidi M, Schwob M, Hassan W, De Maddalena LL, Hugi A, Stucki AO, Dorn P, Marti TM, Wisser O, Stucki JD, Krebs T, Hobi N and Guenat OT Abstract Prolonged exposure to environmental respirable toxicants can lead to the development and worsening of severe respiratory diseases such as…
August 19, 2022
A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip SystemFrontiers in Toxicology Sengupta, A., Roldan, N., Kiener, M., Froment, L., Raggi, G., Imler, T., de Maddalena, L., Rapet, A., May, T., Carius, P., Lehr, C., Geiser, T., Marti, T. M., Stucki, J. D., Hobi, N., & Guenat, O. T. Abstract The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the…
May 07, 2021
Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19Frontiers in Medicine
October 28, 2020
Modelling alveoli on a breathing lung-on-chip in health and diseaseEuropean Respiratory Journal
October 28, 2020
Organoids and lung-on-chip to study SARS-CoV-2-mediated lung injuryEuropean Respiratory Journal
October 28, 2020
Interleukin-2 – induced vascular leak syndrome: clinically relevant in vitro recapitulation with a patient-derived lung-on-chipEuropean Respiratory Journal
October 28, 2020
Modeling alveolar barrier disruption in vitro for sepsis-induced ARDS preclinical studiesEuropean Respiratory Journal
May 05, 2020
Alveolar Dynamics and Beyond – The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and FibrosisFrontiers in Physiology
April 02, 2020
CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lungAJP Lung Cell and Molecular Physiology
January 21, 2020
Clinically relevant tissue scale responses as new readouts from organs-on-a-chip for precision medicineAnnual Review of Analytical Chemistry
January 15, 2020
Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controlsRespiratory Research
January 10, 2020
Air Space Distension Precedes Spontaneous Fibrotic Remodeling and Impaired Cholesterol Metabolism in the Absence of Surfactant Protein CAJR Cell and Molecular Biology
January 10, 2020
Air space distension precedes spontaneous fibrotic remodeling and impaired cholesterol metabolism in the absence of Surfactant Protein CAmerican Journal of Respiratory Cell and Molecular Biology
November 21, 2019
Investigating the toxicological potential of inhaled aerosols in a breathing lung-on-chipEuropean Respiratory Journal
November 21, 2019
A lung-on-chip in vitro approach to study inflammation at the alveolar levelEuropean Respiratory Journal
September 06, 2019
Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipelineEuropean Journal of Pharmaceutics and Biopharmaceutics
Media
March 10, 2022
What is the impact of the 3D stretch?February 01, 2021
AlveoliX in the Swiss Venture Capital Report 2021!December 10, 2020
Organs-on-chip: an alternative to animal experiments?December 02, 2020
Reproducing pulmonary function in the labAugust 01, 2020
20 Bernese start-ups that you must knowJuly 08, 2019
Surviving a Master Thesis… in a start-up!August 31, 2018
Janick Stucki presents lung-on-chip at TEDx in BernMay 01, 2017
Nominated for the CTI Swiss Medtech AwardApril 01, 2017
Cells in the third dimensionDecember 05, 2016
Mini organs to investigate human lung healthSeptember 03, 2015
Simulating the lungsApril 24, 2015
Lung-on-Chip featured in Global Medical DiscoveryApril 01, 2015
Lung-on-Chip in Schweizer Familie