In vitro-ex vivo model systems for nanosafety assessment

European Journal of Nanomedicine Peter Wick, Savvina Chortarea, Olivier T. Guenat, Matthias Roesslein, Janick D. Stucki, Stephanie Hirn, Alke Petri-Fink & Barbara Rothen-Rutishauser Abstract Engineered nanomaterials have unique and novel properties enabling wide-ranging new applications in nearly all fields of research. As these new properties have raised concerns about potential adverse effects for the environment

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A lung-on-a-chip array with an integrated bio-inspired respiration mechanism

Lab on a Chip Andreas O. Stucki, Janick D. Stucki, Sean R. R. Hall, Marcel Felder, Yves Mermoud, Ralph A. Schmid, Thomas Geiser &  Olivier T. Guenat Abstract We report a lung-on-a-chip array that mimics the pulmonary parenchymal environment, including the thin alveolar barrier and the three-dimensional cyclic strain induced by breathing movements. The micro-diaphragm

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